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The Stats Geek Menu Home Posts by Topic Statistics Books Clinical Trial Estimands Jonathan Bartlett On improving the efficiency of trials via linear adjustment for a prognostic score March 13, 2023 by Jonathan Bartlett I’ve recently had the opportunity to spend a little time looking at an interesting approach for improving the efficiency of estimated treatment effects in clinical trials which exploits historical data. In this blog post I’ll give a few thoughts on the results in ‘Increasing the efficiency of randomized trial estimates via linear adjustment for a prognostic score’, by Schuler et al 2022. The paper was published in the International Journal of Biostatistics , and an arXiv pre-print is available here . Read more Categories Randomized controlled trials Tags covariate adjustment , prognostic score 1 Comment G-formula for causal inference via multiple imputation March 2, 2023 January 31, 2023 by Jonathan Bartlett G-formula (sometimes known as G-computation) is an approach |
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